IMMUNOMETABOLISM PRECLINICAL CRO SERVICES
Physiogenex offers immunometabolism preclinical CRO services to evaluate the effects of your drugs on the key role of the immune system on low-grade inflammation in various tissues, leading to metabolic diseases.
Combined with our in vivo experiments, and using Fluorescence-Activated Cell Sorting (FACS) analyses, we validate the efficacy of your treatment:
- Through the characterization of a current panel of innate and adaptive immune cells in metabolic tissues (e.g. adipose tissue, liver, intestine…),
- Simultaneously on both the immune system and metabolic parameters,
- On different tailor-made in vivo models (high fat fed-induced insulin resistance, obesity, NASH in mice, suitable to all mouse models).
Immunometabolism experimental in vivo models
Immunometabolism preclinical services
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