Metabolic disorders affect millions of people worldwide, and their prevalence is increasing from year to year. Modern lifestyles are conducive to the development of obesity, diabetes, but also liver, kidney and heart diseases.

Physiogenex is an expert preclinical CRO for metabolic disorders based in Toulouse, France. For more than 15 years, we have been developing and using our expertise in metabolic diseases to provide reliable preclinical studies for the treatment of such pathologies. We develop innovative models for all metabolic diseases and their complications, as well as a wide range of tests to demonstrate the effectiveness of our clients’ drug candidates.

Founded in 2003, Physiogenex has built its expertise in metabolic diseases (obesity, type 2 diabetes, NASH/MASH fibrosis, diabetic nephropathy, inflammation, dyslipidemia and cardiovascular diseases) over the years with a strong and dedicated team.

Pioneers in the development of predictive animal nutritional models, our aim is to help pharmaceutical, biotechnology and nutraceutical companies to optimize preclinical drug candidates’ studies and reduce the cost and time to market of new therapies.

Our Services

Preclinical drug development

We offer in-house predictive rodent models and radio-tracer based technologies to generate Proof of Concept efficacy data for your drugs targeting metabolic diseases.

Post launched studies

We provide our expertise in detailing the mechanisms by which a drug shows clinical benefits or side-effects, using the right animal model reflecting the human context.


We have a 15-year expertise in the preclinical development of drugs targeting obesity, diabetes and related complications. Whether you need an expertise for a potential project or an expert to set-up and follow your preclinical drug development program, we are here to help.

Based on its scientific skills and R&D program, Physiogenex is continuously developing new innovative animal models for metabolic disorders to offer optimized and innovative customized solutions to our clients. All our knowledge and scientific expertise are applied to provide our customers reliable and quality results.


Physiogenex works with more than 100 biopharmaceutical, nutraceutical and agri-food companies across the world.


Research Tax Credits Accredited CRO

To support our innovative R&D projects, the French Ministry of Higher Education and Research accredited Physiogenex with Research Tax Credits.
All expenses for R&D or innovative projects are eligible to Research Tax Credits.