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- Nephropathy in diabetic db/db mice is accelerated by high protein diet and improved by the SGLT2 inhibitor dapagliflozin.09/27/2019Oct 05 2019Nørgaard SA, Briand F, Sand FW, Galsgaard ED, Søndergaard H, Sørensen DB, Sulpice T.
- Anacetrapib and dalcetrapib05/06/2019Eur J Pharmacol. 2014 October;740: 135–143.Briand F, Thieblemont Q, Muzotte E, Burr N, Urbain I, Sulpice T, Johns DG.
- Evaluation of Antiatherogenic Properties of Ezetimibe Using 3H-Labeled Low-Density-Lipoprotein Cholesterol and 99mTc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet 201705/06/2019NCBIBriand F, Burr N, Urbain I, Mayoux E, Sulpice T.
- Probiotic B420 and prebiotic polydextrose improve efficacy of antidiabetic drugs in mice.09/22/2015Diabetol Metab Syndr. 2015 Sep; 12; 7:75.Stenman L.K, Waget A, Garret C, Briand F, Burcelin R, Sulpice T, Lahtinen S.
- Liraglutide improves hepatic steatosis and metabolic dysfunctions in a 3-week dietary mouse model of non-alcoholic steatohepatitis.11/25/2013World Diabetes Congress, December 2-6, 2013. Melbourne, Australia.Duparc T, Briand F, Trenteseaux C, Mérian J, Combes G, Najib S, Sulpice T, Martinez L, .
- Obeticholic acid raises LDL-cholesterol and reduces HDL-cholesterol in the Diet-Induced NASH (DIN) hamster model.01/05/2018NCBI, Jan 05, 2018.Briand F, Brousseau E, Quinsat M, Burcelin R, Sulpice T.
- Contribution of leukocyte infiltration to lipoperoxidation occurring in the non-ischemic region of the rat heart submitted to permanent left coronary artery occlusion05/24/2012
Sulpice T, Boucher F, Pucheu S, de Leiris J.
- Limiting lipid peroxidation in the nonischemic zone of infarcted rat hearts by indomethacin improves left ventricular function without affecting myocardial healing and remodeling05/24/2012
Sulpice T, Boucher F, de Leiris J.
- EUK-8 a synthetic catalytic scavenger of reactive oxygen species protects isolated iron-overloaded rat heart from functional and structural damage induced by ischemia/reperfusion05/24/2012Cardiovasc Drugs Ther. 1996 Jul;10(3):331-9.Pucheu S, Boucher F, Sulpice T, Tresallet N, Bonhomme Y, Malfroy B, de Leiris J.
- Role of peripheral benzodiazepine receptors in mitochondrial, cellular, and cardiac damage induced by oxidative stress and ischemia-reperfusion05/24/2012J Pharmacol Exp Ther. 2003 Sep;306(3):828-37.Leducq N, Bono F, Sulpice T, Vin V, Janiak P, Fur GL, O'Connor SE, Herbert JM.
- New insights into the pathological role of TNF-alpha in early cardiac dysfunction and subsequent heart failure after infarction in rats05/24/2012Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H340-50.Berthonneche C, Sulpice T, Boucher F, Gouraud L, de Leiris J, O'Connor SE, Herbert JM, Janiak P.
- AT1 receptor blockade prevents cardiac dysfunction after myocardial infarction in rats05/24/2012Cardiovasc Drugs Ther. 2005 Aug;19(4):251-9.Berthonneche C, Sulpice T, Tanguy S, O'Connor S, Herbert JM, Janiak P, de Leiris J, Boucher F.
- Dietary-induced insulin resistance associated with dyslipidemia induces progressive cardiac dysfunction in rats as evidenced by echocardiocardiography05/24/2012Arch Cardiovasc Dis. 2009 Mar;102(S1):22.Grauzam S, Toufektsian MC, Ormezzano O, Jouan MG, Boucher F, Sulpice T.
- Cardiac dysfunction in rats with dietary-induced insulin resistance associated with pharmacologically-induced dyslipidemia.05/02/2013Curr Pharm Des. 2013;19(39):6906-11.Tanguy S, Toufektsian MC, Grauzam S, de Leiris J, Ghezzi C, Boucher F, Sulpice T.
- Berberine increases LDL-cholesteryl ester catabolism and stimulates LDL-derived cholesterol fecal excretion in hyperlipidemic hamsters.05/25/2012European Atherosclerosis Society Congress, May 25-28, 2012, Milan, Italy .Briand F, Thieblemont Q, Muzotte E , Sulpice T.
- Raising HDL with CETP inhibitor Torcetrapib improves insulin resistance and modulates in vivo tissue glucose uptake in dyslipidemic and insulin resistant hamsters.11/25/2013American Heart Association, November 16-20, 2013, Dallas, Texas, USA.Briand F, Thieblemont Q, Muzotte E, Sulpice T.
- Raising HDL with CETP inhibitor Torcetrapib improves glucose homeostasis in dyslipidemic and insulin resistant hamsters.03/24/2014DEUEL conference on Lipids, March 4 – 7, 2014, California, USA.Briand F, Prunet-Marcassus B, Thieblemont Q, Costard C, Muzotte E, Sulpice T.
- Ezetimibe prevents Atherogenesis ahrough increased catabolism and fecal excretion of LDL-cholesterol and reduced atherosclerotic plaque inflammation in ApoE knock-out mice fed a Paigen diet.06/16/2015ATVB, May 7-9, 2015, California, USA.Briand F, Dumas L.S, Broisat A, Ahmadi M, Bacot S, Devoogdt N, Riou L. M, Ghezzi C, Sulpice T.
- Metabolism of cholesterol ester of apolipoprotein B100-containing lipoproteins in dogs: evidence for disregarding cholesterol ester transfer.08/24/2004Eur J Clin Invest. 2004 Aug;34(8):527-34.Bailhache E, Briand F, Nguyen P, Krempf M, Magot T, Ouguerram K.
- Selective uptake of high density lipoproteins cholesteryl ester in the dog, a species lacking in cholesteryl ester transfer protein activity: an in vivo approach using stable isotopes.09/24/2004Comp Biochem Physiol B Biochem Mol Biol. 2004 Aug;138(4):339-45.Ouguerram K, Nguyen P, Krempf M, Pouteau E, Briand F, Bailhache E, Magot T.
- Effects of atorvastatin on high-density lipoprotein apolipoprotein A-I metabolism in dogs.04/24/2006Eur J Clin Invest. 2006 Apr;36(4):224-30.Briand F, Magot T, Krempf M, Nguyen P, Ouguerram K.
- Atorvastatin increases intestinal cholesterol absorption in dogs.07/24/2006J Nutr. 2006 Jul;136(7 Suppl):2034S-2036S.Briand F, Serisier S, Krempf M, Siliart B, Magot T, Ouguerram K, Nguyen P.
- Fenofibrate lowers lipid parameters in obese dogs.08/24/2006Nutr. 2006 Jul;136(7 Suppl):2037S-2040S.Serisier S, Briand F, Ouguerram K, Siliart B, Magot T, Nguyen P.
- Metabolism of high density lipoprotein apolipoprotein A-I and cholesteryl ester in insulin resistant dog: a stable isotope study.01/24/2007Diabetes Obes Metab. 2007 Jan;9(1):139-42.Briand F, Bailhache E, Nguyen P, Krempf M, Magot T, Ouguerram K.
- The hyperenergetic-fed obese dog, a model of disturbance of apolipoprotein B-100 metabolism associated with insulin resistance: kinetic study using stable isotopes.07/24/2008Metabolism. 2008 Jul;57(7):966-72.Briand F, Bailhache E, Andre A, Magot T, Krempf M, Nguyen P, Ouguerram K.
- Both the Peroxisome Proliferator-Activated Receptor Agonist, GW0742, and Ezetimibe Promote Reverse Cholesterol Transport in Mice by Reducing Intestinal Reabsorption of HDL-Derived Cholesterol.05/24/2009Clin trans Sci. 2009; 2:127-133.Briand F, Naik SU, Fuki I, Millar JS, Macphee C, Walker M, Billheimer J, Rothblat G, Rader DJ.
- The use of dyslipidemic hamsters to evaluate drug-induced alterations in reverse cholesterol transport.03/24/2010Curr Opin Investig Drugs. 2010 Mar;11(3):289-97.Briand F.
- Liver X receptor activation promotes macrophage-to-feces reverse cholesterol transport in a dyslipidemic hamster model.04/24/2010J Lipid Res. 2010 Apr;51(4):763-70.Briand F, Tréguier M, André A, Grillot D, Issandou M, Ouguerram K, Sulpice T.
- P2Y13 receptor is critical for reverse cholesterol transport.10/24/2010Hepatology. 2010 Oct;52(4):1477-83.Fabre AC, Malaval C, Ben Addi A, Verdier C, Pons V, Serhan N, Lichtenstein L, Combes G, Huby T, Briand F, Collet X, Nijstad N, Tietge UJ, Robaye B, Perret B, Boeynaems JM, Martinez LO.
- Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.11/24/2010Biochem Pharmacol. 2010 Nov 1;80(9):1450-7.Li X, Millar JS, Brownell N, Briand F, Rader DJ.
- Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice.03/24/2011Gastroenterology. 2011 Mar;140(3):1043-51.Nijstad N, Gautier T, Briand F, Rader DJ, Tietge UJ.
- Diet-induced dyslipidemia impairs reverse cholesterol transport in hamsters.09/24/2011Eur J Clin Invest. 2011 Sep;41(9):921-8.Tréguier M, Briand F, Boubacar A, André A, Magot T, Nguyen P, Krempf M, Sulpice T, Ouguerram K.
- Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters.11/24/2011J Lipid Res. 2011 Nov;52(11):1965-73.Castro-Perez J, Briand F, Gagen K, Wang SP, Chen Y, McLaren DG, Shah V, Vreeken RJ, Hankemeier T, Sulpice T, Roddy TP, Hubbard BK, Johns DG.
- An alternative method to measure in vivo reverse cholesterol transport in hyperlipidemic hamsters.12/10/2011Circulation. 2011; 124: A11835.Briand F, Thieblemont Q, Muzotte E, Sulpice T.
- CETP inhibitor Torcetrapib promotes reverse cholesterol transport in obese insulin-resistant CETP-ApoB100 transgenic mice.12/24/2011Clin Transl Sci. 2011 Dec;4(6): 414-420.Briand F, Thieblemont Q, André A, Ouguerram K, Sulpice T.
- Sitagliptin promotes macrophage-to-feces reverse cholesterol transport through reduced intestinal cholesterol absorption in obese insulin resistant CETP-apoB100 transgenic mice.01/24/2012Diabetes Obes Metab. 2012 Jul;14(7):662-5.Briand F, Thieblemont Q, Burcelin R, Sulpice T.
- High-fat and fructose intake induces insulin resistance, dyslipidemia, and liver steatosis and alters in vivo macrophage-to-feces reverse cholesterol transport in hamsters.05/24/2012J Nutr. 2012 Apr;142(4): 704-709.Briand F, Thieblemont Q, Muzotte E, Sulpice T.
- Upregulating reverse cholesterol transport with cholesteryl ester transfer protein inhibition requires combination with the LDL-lowering drug berberine in dyslipidemic hamsters.11/12/2012Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):13-23.Briand F, Thieblemont Q, Muzotte E, Sulpice T.
- Raising HDL with CETP inhibitor Torcetrapib improves insulin resistance and modulates in vivo tissue glucose uptake in dyslipidemic and insulin resistant hamsters.01/28/2014Atherosclerosis. 2014 233:359-362.Briand F, Prunet-Marcassus B, Thieblemont Q, Costard C, Muzotte E, Sordello S, Sulpice T.
- Anacetrapib and dalcetrapib differentially alters HDL metabolism and macrophage-to-feces reverse cholesterol transport at similar levels of CETP inhibition in hamsters.07/07/2014Eur J Pharmacol. 2014 October;740: 135–143.Briand F, Thieblemont Q, Muzotte E, Burr N, Urbain I, Sulpice T, Johns DG.
- Inverse distribution of uncoupling proteins expression and oxidative capacity in mature adipocytes and stromal-vascular fractions of rat white and brown adipose tissues.05/24/1999FEBS Lett. 1999 Dec 31;464(3):184-8.Prunet-Marcassus B, Moulin K, Carmona MC, Villarroya F, Pénicaud L, Casteilla L.
- Evidence for a direct effect of melatonin on mitochondrial genome expression of Siberian hamster brown adipocytes.05/24/2001J Pineal Res. 2001 Mar;30(2):108-15.Prunet-Marcassus B, Ambid L, Viguerie-Bascands N, Pénicaud L, Casteilla L.
- Melatonin reduces body weight gain in Sprague Dawley rats with diet-induced obesity05/24/2003Endocrinology. 2003 Dec;144(12):5347-52.Prunet-Marcassus B, Desbazeille M, Bros A, Louche K, Delagrange P, Renard P, Casteilla L, Pénicaud L.
- Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice05/24/2005Int J Obes. 2005 Jul;29(7):864-71.Carmona MC, Louche K, Nibbelink M, Prunet B, Bross A, Desbazeille M, Dacquet C, Renard P, Casteilla L, Pénicaud L.
- From heterogeneity to plasticity in adipose tissues: site-specific differences.05/24/2006Exp Cell Res. 2006 Apr 1;312(6):727-36.Prunet-Marcassus B, Cousin B, Caton D, André M, Pénicaud L, Casteilla L.
- Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions.05/24/2007Diabetologia. 2007 Jun;50(6):1277-87.Fyfe MC, White JR, Taylor A, Chatfield R, Wargent E, Printz RL, Sulpice T, McCormack JG, Procter MJ, Reynet C, Widdowson PS, Wong-Kai-In P.
- Metabolic endotoxemia initiates obesity and insulin resistance.07/24/2007Diabetes. 2007 Jul;56(7):1761-72.Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, Neyrinck AM, Fava F, Tuohy KM, Chabo C, Waget A, Delmée E, Cousin B, Sulpice T, Chamontin B, Ferrières J, Tanti JF, Gibson GR, Casteilla L, Delzenne NM, Alessi MC, Burcelin R.
- Adipose tissue sensitivity to radiation exposure.01/24/2009Am J Pathol. 2009 Jan;174(1):44-53.Poglio S, Galvani S, Bour S, André M, Prunet-Marcassus B, Pénicaud L, Casteilla L, Cousin B.
- Pharmacological inhibition of Stearoyl-CoA Desaturase 1 improves insulin sensitivity in insulin-resistant rat models.09/24/2009Eur J Pharmacol. 2009 Sep 15;618(1-3):28-36Issandou M, Bouillot A, Brusq JM, Forest MC, Grillot D, Guillard R, Martin S, Michiels C, Sulpice T, Daugan A.
- An adiponectin-like molecule with antidiabetic properties.10/24/2009Endocrinology. 2009 Oct;150(10):4493-501.Sulpice T, Prunet-Marcassus B, Molveaux C, Cani P, Vitte PA, Graber P, Dreano M, Burcelin R.
- La translocation de bactéries intestinales vers les tissus adipeux initie l’inflammation et le diabète induits par un régime gras chez la souris.03/24/2011Diabetes & Metabolism. 2011 Mar;37(1, S1):A7Chabo C, Amar J, Waget A, Klopp P, Vachoux C, Smirnova N, Bergé M, Sulpice T, Lahtinen S, Ouwehand A, Rautonen N, Sansonetti P, Burcelin R.
- Physiological and pharmacological mechanisms through which the DPP-4 inhibitor Sitagliptin regulates glycemia in mice.09/24/2011Endocrinology. 2011 Aug 15;2(8):3018-29.Waget A, Cabou C, Masseboeuf M, Cattan P, Armanet M, Karaca M, Castel J, Garret C, Payros G, Maida A, Sulpice T, Holst JJ, Drucker DJ, Magnan C, Burcelin R.
- Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.09/28/2011EMBO Mol Med. 2011 Sep;3(9):559-72.Amar J, Chabo C, Waget A, Klopp P, Vachoux C, Bermúdez-Humarán LG, Smirnova N, Bergé M, Sulpice T, Lahtinen S, Ouwehand A, Langella P, Rautonen N, Sansonetti PJ, Burcelin R.
- Effect of the antipsychotic agent amisulpride on glucose lowering and insulin secretion.04/24/2012Diabetes Obes Metab. 2012 Apr;14(4):329-34.Roix JJ, Decrescenzo GA, Cheung PH, Ciallella JR, Sulpice T, Saha S, Halse R.
- Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass.02/22/2013PLOS Biology. 2013 Feb;11(2).Girousse A, Tavernier G, Valle C, Moro C, Mejhert N, Dinel AL, Houssier M, Roussel B, Besse-Patin A, Combes M, Mir L, Monbrun L, Bézaire V, Prunet-Marcassus B.
- Cathepsin S inhibition lowers blood glucose levels in mice.06/13/2014Diabetologia. 2014 August; 57(8): 1674-1683.Lafarge JC, Pini M, Pelloux V, Orasanu G, Hartmann G, Venteclef N, Sulpice T, Shi GP, Clément K, Guerre-Millo M.
- Deletion of Apoptosis Signal-Regulating Kinase 1 (ASK1) Protects Pancreatic Beta-Cells from Stress-Induced Death but Not from Glucose Homeostasis Alterations under Pro-Inflammatory Conditions.12/15/2014PLoS One. 2014; 9(11):e112714.Pepin E, Higa A, Schuster-Klein C, Bernard C, Sulpice T, Guardiola B, Chevet E, Alquier T.