IN VIVO METABOLIC STUDIES FOR DRUG EFFICACY
In vivo metabolic studies are a mandatory step for the development of drugs targeting metabolic disorders. Using our unique and benchmarked animal models, we deliver golden-standard and innovative experiments to demonstrate your drugs’ efficacy. Benefit from our validated radio-tracer based experiments and technical platform to dissect the mechanism by which your drug treats metabolic disorders.
In vivo studies proposed by Physiogenex
- Glucose homeostasis
Glucose tolerance test – GTT
Insulin tolerance test – ITT
Euglycemic hyperinsulinemic clamp
Hyperglycemic clamp
Whole body glucose turnover
In vivo individual tissue glucose uptake
- Lipid metabolism
Lipid tolerance test
Whole body FFA turnover
In vivo individual tissue FFA storage rate
- Heart metabolism
In vivo lipid cardiac metabolism
In vivo glucose cardiac metabolism
- In vivo lipogenesis
- Molecular imaging
Radioactive tagging of molecules of interest
Biodistribution of original molecules
Evaluation of new therapeutic molecules’ efficacy with validated radiotracers
Phenotypic studies and functional studies on small animal models
- Preclinical nuclear imaging services
Benefit from our unique imaging services: innovative translational tracers associated with gamma imager, nanoSPECT/CT, nanoPET/CT, ultrasound imaging services.
- Body composition
Minispec
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