Translating discovery & preclinical results into predictive clinical validation in the field of metabolic and cardiovascular disorders

Physiogenex is a world leading CRO specializing in metabolic and cardiovascular diseases and in predictive functional validation. Physiogenex pioneers the development of radiotracer-based kinetic methods and predictive animal nutritional models, thus providing our partners with the pertinent and reliable discovery and preclinical data they need for successful strategic decision-making. Physiogenex has rapidly achieved global player status by virtue of its unique expertise covering complex metabolic disorders associated with diabetes, obesity, lipid disorders, hypertension and cardiovascular diseases.

Physiogenex now provides the in vivo macrophage-to-feces reverse cholesterol transport experiment
Physiogenex offers the state-of-the-art technique to demonstrate that your compound promotes reverse cholesterol transport and has therefore the potential to prevent atherosclerosis and cardiovascular diseases.
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Physiogenex to present at the KinMet 2009 & ATVB 2009 annual conference in Washington DC, April 28th- May 1, 2009.

Physiogenex will present the effects of CETP inhibition and LXR activation on HDL-cholesteryl esters kinetics in the hypercholesterolemic hamster model.

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Unique expertise in animal nutritional models
A panel of predictive models merging glucose, lipid and/or lipoprotein disorders due to nutritional imbalances, as observed in human populations

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Leader in radiotracers and kinetic studies
A holistic approach to assess therapeutic efficacy on key physiological functions, and to screen potential side effects

Physiogenex is proud to participate in the annual meeting of the EASD. Please contact us to organize a meeting with the Physiogenex team at:

contact@physiogenex.com

Physiogenex is proud to present the effects of Liver-X -Receptor activation on macrophage-to-feces reverse cholesterol transport in dyslipidemic hamsters in vivo.

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