The scientific focus adapted
to express the optimum potential
of your molecule

Unparalleled vision in metabolic disorders and risk assessment expertise for post-marketing studies and drug repositioning.

HeartArteryMacrophageLiverMusclePancreasAdipose Tissue

Preclinical development:
In-house predictive models and tracer technologies enable the generation of Proof of Concept efficacy data for your drugs.

Screening and lead validation utilize a dedicated research platform which combine with our focused scientific vision.

Home > Whole body FFA turnover

Whole body free fatty acid turnover

A gold-standard technique for quantifying drugs affecting FFA oxydation and/or lipogenesis related to type 2 diabetes and obesity.

key benefits

  • In vivo validation on impaired free fatty acid metabolism
  • Sensitivity (15%) sufficient to detect a statistically significant impact of your compound on lipid trafficking: a lack of significant results for plasma FFA does not imply your drug compound doesn’t improve FFA turnover
  • Predictive of individual tissue lipotoxicity

description and parameters

Free fatty acid turnover using radioactive labeled tracers is invaluable for assessing whole body lipid trafficking and circulation in vivo.


  • Rat
  • Mouse

Parameters evaluated

  • FFA fluxes
  • FFA turnover
    • Whole-body oxidation rate
    • Whole-body storage rate
  • Plasma FFA appearance
  • FFA clearance rate

Add-on studies