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Home > Intestinal triglycerides/cholesterol absorption

Intestinal triglycerides / cholesterol absorption

First in vivo proof of concept of the impact of your compound designed to treat type 2 diabetes on cardiovascular complications due to dyslipidemia or hypercholesterolemia, in terms of whole-body lipid homeostasis.

Key benefits

  • In-house validated technique
  • Large-scale screening with an in vivo technique on triglycerides/cholesterol absorption
  • In vivo insights into your compound’s efficacy in inhibiting intestinal lipid absorption
  • Sensitivity to detect a statistically significant impact of your compound on postprandial blood lipid regulation

description

This experiment investigates how triglycerides/cholesterol intestinal absorption is improved with your compound after lipid intake.

Species

  • Rat
  • Mouse
Intestinal triglycerides/cholesterol absorption in awake mice after 5 days of treatment
Intestinal triglycerides/cholesterol absorption in awake mice after 5 days of treatment

Add-on studies