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Home > Insulin tolerance test

insulin tolerance test

First in vivo proof-of-concept method for your compound’s impact on insulin sensitivity.

key benefits

  • Capacity to screen compounds in vivo on a large scale (20-30 compounds/week), with a fast and reproducible in vivo technique
  • Sensitivity (15%) to detect a statistically significant impact of your compound on insulin sensitivity

Description and parameters

The insulin tolerance test shows how diabetic animals regulate their glycemia after insulin stimulation.

Species

  • Rat
  • Mouse

Parameters

  • Plasma glucose

Add-on studies

REFERENCES

Bardoux P. et al, Diabetes, 2005, 54: 1357-63.
Medina Gomez G. et al, Diabetes, 2005, 54: 1706-16.