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Unparalleled vision in metabolic disorders and risk assessment expertise for post-marketing studies and drug repositioning.

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Preclinical development:
In-house predictive models and tracer technologies enable the generation of Proof of Concept efficacy data for your drugs.

Screening and lead validation utilize a dedicated research platform which combine with our focused scientific vision.

Home > Insulin tolerance test

insulin tolerance test

First in vivo proof-of-concept method for your compound’s impact on insulin sensitivity.

key benefits

  • Capacity to screen compounds in vivo on a large scale (20-30 compounds/week), with a fast and reproducible in vivo technique
  • Sensitivity (15%) to detect a statistically significant impact of your compound on insulin sensitivity

Description and parameters

The insulin tolerance test shows how diabetic animals regulate their glycemia after insulin stimulation.


  • Rat
  • Mouse


  • Plasma glucose

Add-on studies


Bardoux P. et al, Diabetes, 2005, 54: 1357-63.
Medina Gomez G. et al, Diabetes, 2005, 54: 1706-16.