The scientific focus adapted
to express the optimum potential
of your molecule

Marketing:
Unparalleled vision in metabolic disorders and risk assessment expertise for post-marketing studies and drug repositioning.

HeartArteryMacrophageLiverMusclePancreasAdipose Tissue

Preclinical development:
In-house predictive models and tracer technologies enable the generation of Proof of Concept efficacy data for your drugs.

Discovery:
Screening and lead validation utilize a dedicated research platform which combine with our focused scientific vision.

Home > Diet Induced Obesity mouse model

diet induced obesity (DIO) mouse model

A model to study pre-diabete type 2 diabetes and obesity

key benefits

  • To mimic gradual body weight gain, and especially visceral fat hypertrophy, as observed in western populations.
  • To select the best drug candidate in a very reproducible model, suitable for screening.
  • To test the efficacy of compounds in a model with sensitivity to all reference compounds tested close to clinical setting.

pharmacological validation

  • Positive reference compounds: metformin and pioglitazone

Fact sheet

DIO mouse 2018 thumbnail
DIO mouse 2018 thumbnail