Parameters evaluated
- Neutral lipids : phytosterol, diglycerides, cholesterol ester, triglycerides
- Fatty acids: SAFA, MUFA, PUFA
Simple and rapid method for assessing your compound's direct impact on intestinal lipid absorption in obesity and/or dyslipidemia.
This method can be used both for medium scale screening purposes and for initial in vivo proof-of-concept.
Key benefits
- Robust in vivo validation on intestinal lipid absorption.
- Large-scale screening with an inexpensive and reproducible in vivo technique
Species
- Rat
- Mouse
Add-on studies
- Lipid tolerance test to obtain insights into whole body lipid absorption and clearance
- Triglycerides /cholesterol absorption to obtain TG/ cholesterol abosrption measurements
