Parameters evaluated
A simple and rapid technique for assessing the direct impact of your compound in type 2 diabetes and/or dyslipidemia.
This method can be used both for medium throughput screening and for initial ex vivo proof-of-concept.
Key benefits
- Ex vivo validation on insulin resistance and lipotoxicity in isolated muscles
- Select your best candidates with an inexpensive, reproducible and rapid technique, before launching in vivo validation
Species
- Rat
- Mouse
Add-on studies
- Free fatty acid turnover assay with specific emphasis on the FFA storage rate in individual tissues, to identify specific tissues targeted by your compound in terms of lipotoxicity
