A nutritional hamster model dedicated to cholesterol & lipoprotein metabolism studies
Key benefits
- To mimic human hypercholesterolemia (high LDL-C levels)
- To select the best drug candidate in a very reproducible model with lipoprotein metabolism similar to humans (e.g.: CETP activity).
- To test the efficacy of compounds in a model with sensitivity tested close to clinical setting.
Animal model
- Background Strain: Golden Syrian hamster
- Gender/Weight: Male/90-110 g
- Diet: chow+cholesterol 0.3%
- Time on diet: 4 weeks
