Diabetes & obesity

Biochemistry

Biochemistry

Ex vivo screening

Muscles / Adipocyte ex vivo glucose uptake

Muscles ex vivo FFA oxydation

Adipocyte ex vivo lipolysis

In vivo screening and profiling

Lipid tolerance test

Glucose tolerance test

Insulin tolerance test

Whole body glucose turnover

Euglycemic hyperinsulinemic clamp

Whole body FFA turnover

In vivo individual tissue glucose uptake

In vivo individual tissue FFA storage rate

Biochemistry

Biochemistry

In vivo screening and profiling

Hyperglycemic clamp

Glucose Tolerance Test + insulin

Glucoincretins assessment in portal vein

In vivo individual tissue glucose uptake

Whole body FFA turnover

Biochemistry

Biochemistry

In vivo screening and profiling

Electrocardiogram

In vivo Lipid cardiac metabolism

In vivo Glucose cardiac metabolism

Heart histology

Biochemistry

Biochemistry

Ex vivo screening

Adipocyte ex vivo glucose uptake

Adipocyte ex vivo lipolysis

In vivo screening and profiling

Body weight

Fat pad weight

Faeces Lipid analyses

Lipid tolerance test

Indirect calorimetry

DEXA

Biochemistry

Biochemistry

Ex vivo screening

Muscles ex vivo FFA oxydation

In vivo screening and profiling

Lipid tolerance test

Whole body FFA turnover

Faeces analyses

VLDL-TG production test

In vivo individual tissue FFA storage rate

FPLC Analyses

HDL turn over

Intestinal triglycerides/cholesterol absorption

Macrophages to feces cholesterol transport

Biochemistry

Biochemistry

Liver inflammation

Liver Lipid profiling

In vivo screening and profiling

In vivo Lipid liver metabolism

In vivo Glucose liver metabolism

Liver histology