Translating discovery & preclinical results into predictive clinical validation in the field of metabolic and cardiovascular disorders

Physiogenex is a world leading CRO specializing in metabolic and cardiovascular diseases and in predictive functional validation. Physiogenex pioneers the development of radiotracer-based kinetic methods and predictive animal nutritional models, thus providing our partners with the pertinent and reliable discovery and preclinical data they need for successful strategic decision-making. Physiogenex has rapidly achieved global player status by virtue of its unique expertise covering complex metabolic disorders associated with diabetes, obesity, lipid disorders, hypertension and cardiovascular diseases.

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Hypercholesterolemic hamster model

An original hamster nutritional model dedicated to mimic human hypercholesterolemia and specifically designed to cholesterol and lipoproteins studies.

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A Race for Life

Physiogenex is a proud sponsor of the 2008 London Marathon.

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Unique expertise in animal nutritional models
A panel of predictive models merging glucose, lipid and/or lipoprotein disorders due to nutritional imbalances, as observed in human populations

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Leader in radiotracers and kinetic studies
A holistic approach to assess therapeutic efficacy on key physiological functions, and to screen potential side effects

June 28, 29, 2008, The Wall Street journal: “The FDA is weighting whether to insist that new diabetes drugs have a positive impact on cardio-vascular disease and life span which are more difficult to measure than current benchmarks such as blood sugar…no drug that regulates sugar levels has yet shown beneficial cardiac effects in Type 2 diabetics”.

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